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Search Results for " topoisomerase i inhibitor 7 "

9

Compounds

Cat No. Product Name Synonyms Targets
T62002 Topoisomerase I inhibitor 7
Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 7 significantly inhibits tumor growth (up to 79%) and increases the lifespan (153%) of mice bearing P388 lympho...
TQ0134 Podocarpusflavone A Topoisomerase
Podocarpusflavone A is a DNA topoisomerase I inhibitor. It has moderated anti-proliferative activity induce cell apoptosis in MCF-7.
T61990 Topoisomerase I/II inhibitor 3
Topoisomerase I/II inhibitor 3 (compound 7) is a potent dual inhibitor of topoisomerase I (Topo I) and II (Topo II) . By inhibiting PI3K /Akt/mTOR signaling pathway, Topoisomerase I/II inhibitor 3 can inhibit cell prolif...
T61501 Topoisomerase I inhibitor 5
Topoisomerase I inhibitor 5 is an efficient inhibitor of topoisomerase I, with an IC50 value. It effectively disrupts DNA and inhibits the activity of topoisomerase I. Moreover, it can induce apoptosis in MCF-7 cells and...
T61717 Topoisomerase I inhibitor 4
Topoisomerase I inhibitor 4 (compound 7a) is a potent inhibitor of topoisomerase I activity. It effectively inhibits the proliferation of various cancer cell lines including HepG2, A549, MCF-7, and HeLa, with IC50 values...
T77873 NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT hydrochloride Topoisomerase
Compound I, NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT hydrochloride, is a topoisomerase I inhibitor that demonstrates effective antibody-drug conjugate (ADC) activity both in vivo and in vitro, with delivery to cells facilit...
T74750 NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT
Compound I, NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT, is a topoisomerase I inhibitor with the capability for targeted delivery to cells via conjugated antibodies. It exhibits effective ADC activity both in vivo and in vitro...
T74751 Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT
Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (Formula V) is a conjugate comprising a potent topoisomerase I inhibitor linked to an antibody agent conjugate (ADC) [1] through a specialized linker.
T36695 TAS-103
TAS-103 is a dual inhibitor of DNA topoisomerase I/II, used for cancer research. TAS-103 is a dual inhibitor of DNA topoisomerase I/II. TAS-103 (0.1-10 μM) is active on CCRF-CEM cells, with an IC50 value of 5 nM. TAS-103...
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